Science Abstracts
Recent advances in the discovery of non-peptidic direct renin inhibitors as antihypertensives: new patent applications in years 2000 – 2008
June 2008
June 2008
Authors : Fumiaki Yokokawa1 , Jürgen Maibaum2
Affliation :
1Novartis Pharma KK, Tsukuba Research Institute, Ohkubo 8 Tsukuba 300-2611, Japan ; ; fumiaki.yokokawa@novartis.com
2Novartis Pharma AG, Novartis Campus, Forum 1, CH-4056 Basel, Switzerland
DOI : 10.1517/13543776.18.6.581
Published in : Expert Opin. Ther. Patents Volume 18 Issue 6 2008 pages 581 602
Subject:
Keywords: aliskiren , antihypertensive , aspartic protease , flap region , piperidine , RAAS , renin-angiotensin-aldosterone system , renin inhibitor
Abstract
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